Anticoagulation is a critical component in the treatment of cardiovascular diseases. Large randomised controlled trials have demonstrated that direct oral anticoagulants (DOACs) are effective and safe ...
The global pandemics of plague and smallpox in the Middle Ages claimed hundreds of millions of lives. In this era, long before the concepts of pathogens and infectious diseases were established, ...
Atrial fibrillation (AF) is the most common arrhythmia and is a leading cause of stroke and heart failure yet often remains undiagnosed. Screening has been proposed to identify asymptomatic AF and ...
Obesity is an independent driver of cardiovascular disease (CVD), mediated through adverse haemodynamic loading, insulin resistance, systemic inflammation, endothelial dysfunction and prothrombotic ...
Sick sinus syndrome (SSS) is a relatively benign cardiac conduction system disorder that can reduce patients’ quality of life by limiting exercise capacity or causing dizziness, fatigue, palpitations ...
10 The George Institute for Global Health, School of Public Health, Imperial College London, London, UK Background Cardiovascular risk is underassessed in women. Many women undergo screening ...
International Centre for Circulatory Health, 10th Floor QEQM Wing, St Mary’s Hospital, and Imperial College Paddington and Clinical Pharmacology, NHLI, Imperial College of Science, Technology & ...
Background Rapid triage of patients presenting with chest pain is essential for early diagnosis and safe disposition. The European Society of Cardiology (ESC) 0/1-hour hs-cTn algorithm has shown ...
1 King's College London British Heart Foundation Centre of Research Excellence, The Rayne Institute, St. Thomas’ Hospital Campus, London, UK 2 National Institute for Health Research Biomedical ...
Aims In people with heart failure (HF), a high body mass index (BMI) has been linked with better outcomes (‘obesity paradox’), but there is limited evidence in community populations across long-term ...
At present there is no universally accepted nomenclature for congenital cardiac malformations. Much of the controversy results from failure to distinguish the structural connections of the heart from ...
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