A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries ...

Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

Researchers have identified a distinct and reproducible gene expression program associated with neurotransmission in the ...

Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

Inside a diseased cell, the genes are in chaos. Some are receiving signals to overproduce a protein. Others are reducing ...

Researchers identify a gene expression program in the living human brain that tracks with real-time neurotransmission, ...