The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Scientists have uncovered a surprising secret about our DNA: it’s not a static blueprint, but a constantly shifting, folding structure that helps control how genes turn on and off. Researchers at the ...

CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

Forbes contributors publish independent expert analyses and insights. The period between the 1920s and 1950s was a time of significant progress and exciting discoveries in gene therapy history and ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

A wave of AI foundation models built on plant DNA sequences is giving researchers new tools to annotate genomes, predict gene ...